|AmeriGlo Hackathorn sights on my Glock 19 slide|
For me personally, I generally have two main criteria: I want a front sight that draws my eye and can be seen under a variety of light conditions, and I want a rear sight that has a ledge to allow me to rack the slide one-handed if I need to.
The two sights that I tend to rely on are the Redback One (RB-1) sights designed in conjunction with 10-8 Performance, and the AmeriGlo Hackathorn (GL-433) sights. The RB-1 sights reside on my Glock 17, and the Hacks reside on my Glock 19. The RB-1 sights were my first sights that I ever changed out on a pistol, and at the time, they were ideal. The front sight is a narrow blade with a tritium insert. The rear sight is plain black, serrated to reduce glare, with a wide notch to allow me to pick up the front sight faster. It has just enough of a ledge to catch the edge of a holster to rack the slide with a single hand. The combination of the narrow front and wide rear is not ideal for longer-range precision shots, but really does lend itself to fast sight acquisition at normal self-defense ranges. The Hackathorn sights are similar, but an improvement, in my opinion. The front sight is still tritium, but it's surrounded by a fiber optic ring that increases the sight's visibility in brighter conditions where the tritium isn't effective. The rear sight is similar to the RB-1, but with a slightly larger ledge. Both rear sights slide into the standard Glock rear sight cut and are held in place with a set screw. I used blue Loc-Tite on the set screw, but both sights fit into the sight cut tight enough that I'm not really worried about them moving. Both sights shoot point of aim/point of impact.
Both sight sets are excellent choices, but if I had to choose a favorite, it would be the Hacks. The addition of the fiber optics to the tritium insert really, really draws the eye, and is more applicable in a wider variety of situations. I highly recommend them to anyone looking to replace their stock Glock sights.